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Circulatory Shock | New England Journal of Medicine
See results only from nejm.orgOct 31, 2013 · Circulatory shock is present when physical signs and changes in laboratory values suggest tissue hypoperfusion. This article in the Critical Care Medicine series reviews the …
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Clinical Trials in Cardiogenic Shock: - JACC: Advances
Open Research Questions, Challenges in Clinical Trials in Cardiogenic Shock, and Opportunities in Conducting High-Quality Research Trials. AMI-CS = acute myocardial infarction-related cardiogenic shock; CRRT = continuous renal …
Standardized Definitions for Cardiogenic Shock …
Oct 2, 2023 · Several in-person and virtual meetings were convened between 2020 and 2022 to discuss the need for developing the standardized definitions required for evaluation of mechanical circulatory support devices in clinical …
Shock Clinical Trials - Mayo Clinic Research
The purpose of this study is to determine whether the combination of Ascorbic Acid (Vitamin C), Thiamine (Vitamin B1), and Corticosteroids improves the trajectory of organ failure and …
Cardiogenic Shock | Journal of the American Heart …
Apr 5, 2019 · The SHOCK (Should We Emergently Revascularize Occluded Coronaries for Cardiogenic Shock) and intra‐aortic balloon pump (IABP)‐SHOCK II trials used systolic blood pressure (SBP) measurements of <90 mm Hg for …
The Global Applicability of the DanGer Shock Trial
Aug 28, 2024 · The DanGer Shock (Microaxial Flow Pump in Infarct-Related Cardiogenic Shock) trial was an important study in this space that was successfully concluded after 10 years because of slow recruitment. 1 The trial …
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Clinical Trials in Cardiogenic Shock - PubMed Central (PMC)
Open Research Questions, Challenges in Clinical Trials in Cardiogenic Shock, and Opportunities in Conducting High-Quality Research Trials. AMI-CS = acute myocardial infarction-related …
Mechanical circulatory support in acute myocardial infarction and ...
Cardiogenic shock (CS) is a frequent and deadly complication of acute myocardial infarction (AMI). 1 – 3 With advancements in medical therapy, early revascularization and regional …
Trials, Tribunals, and Opportunities in Cardiogenic …
Cardiogenic shock (CS), from acute myocardial infarction (AMI) or non-AMI etiologies, continues to be associated with nearly 40% to 50% in-hospital mortality and continued long-term morbidity if the patient survives the initial …
Cardiogenic Shock Intravascular Cooling Trial (CHILL …
In this open-label, randomized controlled pilot trial, 20 patients with hemodynamic criteria for CS were assigned to standard of care plus TTC vs standard of care alone. The primary outcome was a composite safety outcome, including well …
Extracorporeal Membrane Oxygenation in the …
Nov 6, 2022 · The ECMO-CS trial (Extracorporeal Membrane Oxygenation in the Therapy of Cardiogenic Shock) aimed to compare immediate implementation of VA-ECMO versus an initially conservative therapy (allowing downstream use …
Breaking Down Cardiogenic Shock: An Analytical Reflection on …
Feb 1, 2025 · To explore this further, we conducted a comparative analysis of the 30-day and 6-month mortality rates from the DanGer-SHOCK and ECLS-SHOCK trials, examining …
Cardiogenic Shock: A Systematic Review of Clinical Trials
The primary endpoints were clinical, focusing on mortality and restoration of cardiac output or cardiac index. Methodological quality varies in the trials focused on pharmacologic therapy. …
ECLS-SHOCK and DanGer Shock: Implications for Optimal …
Jan 15, 2025 · A randomized clinical trial to evaluate the safety and efficacy of a percutaneous left ventricular assist device versus intra-aortic balloon pumping for treatment of cardiogenic shock …
Long-term 5-year outcome of the randomized IMPRESS in …
We therefore performed 5-year follow-up of the IMPRESS in Severe Shock trial to assess differences in clinical outcomes and functional status between pMCS and IABP supported …
Clinical Outcomes Of Temporary Mechanical Circulatory Support …
Cardiogenic shock (CS) is a heterogeneous syndrome with varied clinical presentations and outcomes. Two primary etiologies for CS include acute myocardial infarction (AMI) and heart …
Microaxial Flow Pump Effects in Infarct-Related Cardiogenic Shock
Importance Mechanical circulatory support with a microaxial flow pump (MAFP) has been shown to improve survival in ST-elevation myocardial infarction–induced cardiogenic shock (STEMI …
Trials for Mechanical Circulatory Support Devices in Cardiogenic …
Sep 15, 2022 · A randomized clinical trial to evaluate the safety and efficacy of a percutaneous left ventricular assist device versus intra-aortic balloon pumping for treatment of cardiogenic shock …
A Personal Perspective on Circulatory Support and Outcomes in …
Nov 10, 2024 · A randomized clinical trial to evaluate the safety and efficacy of a percutaneous left ventricular assist device versus intra-aortic balloon pumping for treatment of cardiogenic shock …
Extracorporeal Membrane Oxygenation in the Therapy of …
Nov 6, 2022 · The ECMO-CS trial (Extracorporeal Membrane Oxygenation in the Therapy of Cardiogenic Shock) aimed to compare immediate implementation of VA-ECMO versus an …
Lactate infusion improves cardiac function in a porcine model of ...
1 day ago · Cardiogenic shock (CS) is a complex and life-threatening clinical syndrome with an in-hospital mortality of 30–50% despite treatment . CS is often caused by ischemia due to …
The Management of Severe Sepsis and Septic Shock: A Novel
Mar 8, 2025 · Purpose of Review This review highlights recent advances in the treatment of severe sepsis and septic shock, emphasizing new strategies aimed at improving overall …
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